Antihistamine Drug That Works

Promethazine, which belongs to the phenothiazine group of drugs, works by changing your brain’s chemical actions. It is effective in treating allergy symptoms as well as motion sickness.

Marketed under the brand names Pentazine and Phenergan, Promethazine is an antihistamine that belongs in the phenothiazine group of drugs. Promethazines are available in tablets and suppositories and work by changing the chemical actions of your brain.

As antihistamine, the Promethazine blocks the effects of your body’s naturally occurring histamine. It is used to treat allergy symptoms such as sneezing, runny nose, itching, hives, itchy skin rashes and watery or itchy eyes. Additionally, it also treats vomiting and nausea or post-surgical pain and prevent motion sickness. You can also use the drug as a sleep aid or sedative.

Dosages and Indications:

Promethazine tablet is available in 12.5 milligrams, 25 milligrams and 50 milligrams. Meanwhile, each rectal suppository is available in 12.5 milligrams, 25 milligrams and 50 milligrams.

Whether orally or suppository, Promethazine is useful for vasomotor rhinitis, seasonal and perennial allergic rhinitis, uncomplicated or mild allergic skin manifestations of angioedema or urticaria, relieving allergic reactions to plasma or blood, anaphylactic reactions, postoperative sedation, pre-operative sedation, obstetric sedation, antiemetic therapy in post-surgery, adult and children sedation, control and prevention of vomiting and nausea associated with anesthesia and surgery.

Contraindications:

Promethazine is not recommended for use in treating pneumonia, asthma or any lower respiratory tract diseases. If you are experiencing uncontrollable movements of the eyes, lips, face, arms, legs, tongue, arm and face or twitching, these are some early signs of dangerous adverse reactions. Take note that the drug should not be given to children 2 years and below because it can cause death or severe breathing problems. Some conditions that you need to tell your doctor before you take this drug are history of seizures, severe asthma, kidney or liver disease, chronic obstructive pulmonary disease, high blood pressure, heart disease and sleep apnea.

Side Effects:

The most identified side effect of this drug is drowsiness. Other adverse effects are somnolence, blurred vision, confusion, disorientation, decreased or increased blood pressure, faintness, bradycardia, tachycardia, vomiting, nausea, janduice, leucopenia, angioneurotic edema and hyperexcitability. In rare cases, Promethazine may cause respiratory depression, agitated behavior, delirium and nightmares.